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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGFR3
All Species:
12.42
Human Site:
Y152
Identified Species:
24.85
UniProt:
P22607
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22607
NP_000133.1
806
87710
Y152
G
V
D
T
G
A
P
Y
W
T
R
P
E
R
M
Chimpanzee
Pan troglodytes
XP_521622
819
91776
Y155
S
N
N
K
R
A
P
Y
W
T
N
T
E
K
M
Rhesus Macaque
Macaca mulatta
XP_001101108
806
87642
Y152
G
V
D
T
G
A
P
Y
W
T
R
P
E
R
M
Dog
Lupus familis
XP_545926
833
90729
Y179
G
V
L
T
G
A
P
Y
W
T
R
P
E
R
M
Cat
Felis silvestris
Mouse
Mus musculus
Q61851
801
87739
P150
G
A
P
Y
W
T
R
P
E
R
M
D
K
K
L
Rat
Rattus norvegicus
Q04589
822
91806
K145
E
K
E
T
D
N
T
K
P
N
R
R
P
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P18460
806
89712
P150
G
V
P
F
W
T
R
P
D
K
M
E
K
K
L
Frog
Xenopus laevis
O42127
802
89497
R141
T
E
D
R
E
P
P
R
W
T
Q
P
E
R
M
Zebra Danio
Brachydanio rerio
Q9I8X3
800
89698
P144
G
N
G
N
A
E
A
P
Y
W
T
R
S
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07407
729
82568
G129
T
L
N
C
H
A
L
G
N
P
E
P
N
I
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10656
1040
118938
D263
N
K
E
D
E
E
E
D
Y
S
V
S
Q
P
V
Sea Urchin
Strong. purpuratus
Q26614
972
110463
Y271
L
E
L
E
T
G
P
Y
N
E
T
E
E
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.2
99.1
89.3
N.A.
92.4
62.9
N.A.
N.A.
80.1
70.5
73.8
N.A.
37.5
N.A.
31.3
35.4
Protein Similarity:
100
77.5
99.2
91.9
N.A.
94.7
76.2
N.A.
N.A.
87.5
79.4
82.3
N.A.
54
N.A.
46.6
50
P-Site Identity:
100
46.6
100
93.3
N.A.
6.6
13.3
N.A.
N.A.
13.3
53.3
6.6
N.A.
13.3
N.A.
0
20
P-Site Similarity:
100
60
100
93.3
N.A.
26.6
20
N.A.
N.A.
33.3
60
13.3
N.A.
26.6
N.A.
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
42
9
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
25
9
9
0
0
9
9
0
0
9
0
9
0
% D
% Glu:
9
17
17
9
17
17
9
0
9
9
9
17
50
9
9
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
50
0
9
0
25
9
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
17
0
9
0
0
0
9
0
9
0
0
17
25
0
% K
% Leu:
9
9
17
0
0
0
9
0
0
0
0
0
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
42
% M
% Asn:
9
17
17
9
0
9
0
0
17
9
9
0
9
0
0
% N
% Pro:
0
0
17
0
0
9
50
25
9
9
0
42
9
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% Q
% Arg:
0
0
0
9
9
0
17
9
0
9
34
17
0
34
9
% R
% Ser:
9
0
0
0
0
0
0
0
0
9
0
9
9
0
0
% S
% Thr:
17
0
0
34
9
17
9
0
0
42
17
9
0
0
9
% T
% Val:
0
34
0
0
0
0
0
0
0
0
9
0
0
9
9
% V
% Trp:
0
0
0
0
17
0
0
0
42
9
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
42
17
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _